Modern Physical Organic Chemistry
Phys. Org. Chem. has always been one of my favourite subjects. As I graduated from school and college into university for my master’s, I began to realise that it represents not so much a separate topic as a philosophy and approach; to treat chemical and biological systems from the perspective of structure, conformation, and reactivity, which are after all the most fundamental aspects of any such system. I reached the conclusion that phys org chem is a truly interdisciplinary framework, and any one who has a solid background in it can be a good computational chemist, synthetic organic chemist, and/or bioorganic/biochemist.
Unfortunately, all the classic phys org books until now have been of the ‘pure’ kind, focusing on mechanism and reactivity, but not discussing the interdisciplinary nature of the topic, especially for biological systems. My wait is over; Modern Physical Organic Chemistry by Dennis Dougherty and Eric Anslyn has completely and satisfactorily reinvented the phys org chem textbook. Now, one can look to a wholesome treatment of phys org as a multidisciplinary, fundamental, and exciting approach to both chemistry and biology. The book is worth its price, and covers the gamut of topics, including basic ones like mechanisms and bonding, but also is interspersed with lots of boxes and discussions explaining the applications of basic phys org concepts to host guest systems, proteins and nucleic acids, strained molecules, and materials science. Fantastic reference. It should make you a well-rounded chemist, which is the need of the day in today’s era of collaborative research. (customer review).
This is the first modern textbook, written in the 21st century, to make explicit the many connections between physical organic chemistry and critical fields such as organometallic chemistry, materials chemistry, bioorganic chemistry, and biochemistry. In the latter part of the 20th century, the field of physical organic chemistry went through dramatic changes, with an increased emphasis on noncovalent interactions and their roles in molecular recognition, supramolecular chemistry, and biology; the development of new materials with novel structural features; and the use of computational methods. Contemporary chemists must be just as familiar with these newer fields as with the more established classical topics. This completely new landmark text is intended to bridge that gap. In addition to covering thoroughly the core areas of physical organic chemistry – structure and mechanism – the book will escort the practitioner of organic chemistry into a field that has been thoroughly updated . The foundations and applicabilities of modern computational methods are also developed. Written by two distinguished researchers in this field, Modern Physical Organic Chemistry can serve as a text for a year-long course targeted to advanced undergraduates or first-year graduate students, as well as for a variety of shorter courses on selected aspects of the field. It will also serve as a landmark new reference text, and as an introduction to many of the more advanced topics of interest to modern researchers. An accompanying Student Solutions Manual will become available.
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Tags: Active Oxygen, Laboratory Manual, Modern Structural Chemistry, Structure-Function Correlations, Techniques of Chemistry
